个人简介
2005年于内蒙古大学获理学学士学位;同年保送中国科学院成都有机化学研究所硕博连读,师从龚流柱教授从事不对称催化反应研究,于2010年7月获有机化学博士学位;2010年7月-2013年1月在美国纽约州立大学布法罗分校Qing Lin教授课题组从事化学生物学的博士后研究。曾获得2010年度“中国科学院朱李月华优秀博士生奖学金”、2011年度“中国科学院百篇优秀博士论文奖”。先后在J. Am. Chem. Soc; Angew. Chem. Int. Ed; ACS Chemical Biology; Org. Biomol. Chem; Chem. Commun.等国际一流学术期刊上发表多篇论文。
目前主要开展有机合成方法学,功能有机材料及化学生物学研究,包括新型生物相容性反应的开发,功能有机荧光分子的设计、合成及应用研究。
在研项目
1.国家自然科学基金面上项目,在研,主持.
2.中央高校重点项目,在研,主持.
3.williamhill威廉希尔官网科研启动基金,在研,主持.
4.国家自然科学基金青年项目,已结题,主持.
5.陕西省自然科学基金青年项目,已结题,主持.
6.中央高校一般项目,已结题,主持.
代表性成果
1.Nan Li,Yanyan Liu, Yan Li, Jiabao Zhuang, Rongrong Cui, Qian Gong, Na Zhao*, Ben Zhong Tang*, Fine Tuning of Emission Behavior, Self-Assembly, Anion Sensing, and Mitochondria Targeting of Pyridinium-Functionalized Tetraphenylethene by Alkyl Chain Engineering.ACS Appl. Mater. Interfaces., 2018, 10, 24249–24257.
2.Rongrong Cui, Yuanchao Lv, Yong Sheng Zhao, Na Zhao*,Nan Li*, Solid-state fluorescent materials based on coumarin derivatives: polymorphism, stimuli-responsive emission, self-assembly and optical waveguides.Mater. Chem. Front., 2018,2, 910-916. (Materials Chemistry FrontiersHOT articles for 2018)
3.Ruixue Zhang, Pengfei Li, Wenjuan Zhang,Nan Li*, Na Zhao*, A highly sensitive fluorescent sensor with aggregation-induced emission characteristics for the detection of iodide and mercury ions in aqueous solution.J. Mater. Chem. C., 2016, 4, 10479-10485
4.Nan Li*,Honglian Feng, Qian Gong, Chunxiao Wu, Hao Zhou, Zhiyan Huang, Jun Yang, Xiaohua Chen, Na Zhao, BINOL-based chiral aggregation-induced emission luminogens and their application in detecting copper(II) ions in aqueous media.J. Mater. Chem. C., 2015, 3, 11458-11463
5.Na Zhao, Qian Gong, Ruixue Zhang, Jun Yang, Zhiyan Huang,Nan Li*, Ben Zhong Tang, A fluorescent probe with aggregation-induced emission characteristics for distinguishing homocysteine over cysteine and glutathione.J. Mater. Chem. C., 2015, 3, 8397-8402
6.Nan Li, Carlo P. Ramil, Reyna K. V. Lim, and Qing Lin*, A Genetically Encoded Alkyne Directs Palladium-Mediated Protein Labeling on Live Mammalian Cell Surface.ACS Chem. Biol., 2015, 10, 379-384.
7.Nan Li, Reyna K. V. Lim, Selvakumar Edwardraja, Qing Lin*, Copper-Free Sonogashira Cross-Coupling for Functionalization of Alkyne-Encoded Proteins in Aqueous Medium and in Bacterial Cells.J. Am. Chem. Soc., 2011.133. 15316-15319(Highlighted inChemBioChem. 2012, 13, 1728-1731).
8.Nan Li, Xiao-Hua Chen, Shi-Ming Zhou, Shi-Wei Luo, Jin Song, Lei Ren and Liu-Zhu Gong*Asymmetric Amplification in Phosphoric Acid Catalyzed Reactions.Angew Chem Int Ed.,2010, 49, 6378-6381. (Highlighted inSynfacts. 2010, 10, 1189-1189).
9.Nan Li, Jin Song, Xi-Feng Tu, Bin Liu, Xiao-Hua Chen and Liu-Zhu Gong*,Organocatalytic Asymmetric Intramolecular [3+2] Cycloaddition: A Straightforward Approach to Access Multiply Substituted Hexahydrochromeno[4,3-b]pyrrolidine Derivatives in High Optical Purity.Org.Biomol. Chem., 2010, 8, 2016-2019.
10.Nan Li,Xiao-Hua Chen, Jin Song, Shi-Wei Luo*, Wu Fan and Liu-Zhu Gong*,Highly Enantioselective Organocatalytic Biginelli and Biginelli-Like Condensations: Reversal of the Stereochemistry by Tuning the 3,3′-Disubstituents of Phosphoric Acids.J. Am. Chem. Soc., 2009.131. 15301-1531
11.Jingnan Zhang, Hui Kang,Nan Li, Shiming Zhou, Huaming Sun, Shiwei Yin, Na Zhao, Ben Zhong Tang, Organic solid fluorophores regulated by subtle structure modification: color-tunable and aggregation-induced emission.Chem. Sci., 2017, 8, 577-582.
12. Reyna K.V. Lim,Nan Li, Carlo P. Ramil and Qing Lin*, Fast and sequence-specific palladium-mediated cross-couping reaction identified from phage display.ACS Chem. Biol., 2014, 9, 2139-2148.
13. Gang Cheng, Reyna K. V. Lim,Nan Li, Qing Lin*, Storable Palladacycles for Selective Functionalization of Alkyne-Containing Proteins.Chem. Commun., 2013.49. 6809-6811.